A new study focusing on women and their susceptibility to Alzheimer's disease revealed that a hormone derived from a visceral fat known as adiponectin may be a risk factor that increases the changes of women developing the cognitive disease.
Published in Online First by the Archives of Neurology, a JAMA/Archives journal, the study also revealed the number of people affected by dementia across the world is estimated to double over the next 20 years from the current total of 36 million.
"It is well established that insulin signaling is dysfunctional in the brains of patients with AD, and since adiponectin enhances insulin sensitivity, one would also expect beneficial actions protecting against cognitive decline," the authors wrote in the study. "Our data, however, indicate that elevated adiponectin level was associated with an increased risk of dementia and AD in women."
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