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Researchers discover method of strengthening bones

02/09/12

A research team led by UC Davis Health System scientists recently developed a technique to increase bone formation and strength after testing the method on mice.

The new technique is said to enhance bone growth by using a molecule that directs the body's stem cells to the surface of bones when injected into the bloodstream.

The results of the study were recently published online in biomedical journal Nature Medicine. Researchers used a mouse model of osteoporosis to demonstrate the new method of strengthening bones.

"These results are very promising for translating into human therapy," said Jan Nolta, professor of internal medicine, an author of the study and director of the UC Davis Institute for Regenerative Cures. "We have shown this potential therapy is effective in rodents, and our goal now is to move it into clinical trials."

After the 12-week study, the bone mass in the mice's femur and vertebrae increased and bone strength improved compared with the control mice that didn't receive any treatment.

More than 10 million Americans are estimated to have osteoporosis, and 34 million are estimated to have low bone density, which should encourage older Americans to secure a life insurance policy.

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